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Gene : |
KDM1A |
Gene ID : |
23028 |
Uniprot ID : |
O60341 |
Alternative Name : |
KDM1A, AOF2, KDM1, KIAA0601, LSD1 |
Format : |
Purified |
Amount : |
100 µg |
Isotype : |
Rabbit IgG |
Immunogen Information : |
A partial length recombinant LSD1 protein (amino acids 97-328) was used as the immunogen for this antibody. |
LSD1 or KDM1A (lysine (K)-specific demethylase 1A) gene encodes a nuclear protein which contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes. LSD1 or KDM1A is a demethylase that acts on both Lys 4 and 9 of histone H3. Consequently depending upon the use it may act as a co-activator or a co-repressor. It may have a role in the repression of neuronal genes. Two isoforms of LSD1 have been reported which are produced by alternative splicing. LSD1 has more or less ubiquitous expression.
Western blot analysis: 0.5-2.0 µg/ml, Immunohistochemical analysis: 5 µg/ml