|
|
| Gene : |
Ebi3 |
| Gene ID : |
50498 |
| Uniprot ID : |
O35228 |
| Alternative Name : |
Ebi3, Il27b |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
ABM2C40 |
| Isotype : |
Rat IgG2b Kappa |
| Immunogen Information : |
A full length recombinant mEBI3 protein was used as the immunogen for this antibody. |
Epstein-Barr Virus?Induced Gene 3 (EBI3) is an immune regulator that has been associated with the pathogenesis of inflammatory bowel disease. EBI3, as part of the immunosuppressive IL-35 cytokine, plays an important role in the regulation of intestinal immune responses by controlling overwhelming T-cell activation. EBI3 deficiency does not lead to changes in intestinal pathology in trinitrobenzene sulfonic acid colitis, but is protective in oxazolone-induced colitis.
Western blot analysis: 2-4 µg/ml
