|
|
Gene : |
TLR8 |
Gene ID : |
51311 |
Uniprot ID : |
Q9NR97 |
Alternative Name : |
TLR8, UNQ249/PRO286 |
Format : |
Purified |
Amount : |
100 µg |
Clone name : |
ABM15F6 |
Isotype : |
Mouse IgG1 Kappa |
Immunogen Information : |
A partial length recombinant TLR8 protein (amino acids 750-900) was used as the immunogen for this antibody. |
Toll like receptor 8, also known as CD288, is a member of TLR family. It plays an important role in sensing phagocytosed pathogen. TLR8 recognizes ssRNA and recruits MyD88 and leads to the activation of transcription factor NF-kappa B. TLR8 TLR8 has two splice variants, viz., TLR8v1 and TLR8v2 and one missense variant, termed G or A1G allele of TLR8. TLR8v1 has additional 19 amino acids in the N-terminus. It is predominantly expressed in lung and peripheral blood leukocytes.
FACS analysis: 0.5-1 µg/10^6 cells