|
|
| Gene : |
TLR2 |
| Gene ID : |
7097 |
| Uniprot ID : |
O60603 |
| Alternative Name : |
TLR2, TIL4 |
| Format : |
Purified |
| Amount : |
100 Test |
| Clone name : |
ABM3A87 |
| Isotype : |
Mouse IgG1 Kappa |
| Immunogen Information : |
A partial length recombinant TLR2 protein (amino acids 180-420) was used as the immunogen for this antibody. |
TLR2 (Toll-Like Receptors 2) is a member of the TLR (Toll-like receptor) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLR2 forms heterodimers with TLR1 and TLR6, which is the initial step in a cascade of events leading to significant innate immune responses, development of adaptive immunity to pathogens and protection from immune sequelae related to infection with these pathogens. TLR2 also interacts with a large number of non-TLR molecules, allowing for recognition of a great number and variety of PAMPs (pathogen-associated molecular patterns). TLR2 expression has been detected in immune cells, endothelial, and epithelial cells.
FACS analysis: 0.5 -1 µg/10^6 cells
